This Bisquick Breakfast Casserole is a warm, tasty dish packed with eggs, cheese, and your choice of veggies or meats. It’s super easy to whip up and perfect for mornings!
Trust me, everyone will love digging into this cheesy goodness. Plus, you can even make it ahead of time! Breakfast in a breeze? Yes, please! 😋
Key Ingredients & Substitutions
Bisquick Baking Mix: This is the star of the show, giving the casserole its fluffy texture. If you don’t have Bisquick, you can make a homemade blend using equal parts flour, baking powder, and a pinch of salt.
Milk: Whole milk makes it creamy, but you can use low-fat milk or a non-dairy milk like almond or oat milk if you’re looking for a lighter option.
Breakfast Sausage: I love using pork sausage for its rich flavor, but turkey sausage or even crumbled tofu can be great substitutes for a lighter or meat-free dish.
Cheddar Cheese: Sharp cheddar gives a nice bite, but feel free to swap in Monterey Jack or mozzarella for a milder flavor. A blend of cheeses can also make it fun!
Onion: Chopped onions add great flavor, but you can simply skip them or use green onions for a milder taste.
How Do You Ensure the Casserole Is Perfectly Set?
Getting the right consistency in this casserole is crucial. Start by preheating your oven and greasing your pan well. This helps with even cooking and prevents sticking.
- Mix the ingredients until just combined to avoid overmixing, which can make the casserole dense.
- Watch the baking time; every oven is different. It should set in the middle and the top should be golden brown.
- If unsure, you can use a toothpick or knife to check doneness. If it comes out clean, you’re good to go!
Let it cool for a few minutes before slicing; this helps it hold its shape better when you cut it!

Delicious Bisquick Breakfast Casserole
Ingredients You’ll Need:
Base Ingredients:
- 2 cups Bisquick baking mix
- 1 cup milk
- 4 large eggs
Flavor Additions:
- 1/2 pound breakfast sausage, cooked and crumbled
- 1 1/2 cups sharp cheddar cheese, shredded
- 1/4 cup onion, finely chopped (optional)
- 1/4 teaspoon salt
- 1/4 teaspoon black pepper
Garnish:
- Fresh parsley or chives, chopped (optional)
How Much Time Will You Need?
This Bisquick Breakfast Casserole takes about 10 minutes to prepare and 35 to 45 minutes to bake. In total, you can expect to spend around 50 to 60 minutes from start to finish, making it a quick and easy option for breakfast or brunch!
Step-by-Step Instructions:
1. Preheat and Prepare:
Start by preheating your oven to 350°F (175°C). While that’s warming up, take a 9×9-inch baking dish (or a similar-sized casserole dish) and grease it with some cooking spray so that your casserole doesn’t stick later.
2. Mix the Base:
In a large mixing bowl, whisk together the Bisquick baking mix, milk, eggs, salt, and pepper until everything is nicely blended and smooth. This forms the base of our casserole that binds it all together!
3. Add Flavorful Ingredients:
Into the same bowl, stir in the cooked, crumbled breakfast sausage and 1 cup of the shredded cheddar cheese. If you’re using onions, toss those in too! Mix everything well to combine, ensuring all the ingredients are evenly distributed.
4. Pour and Spread:
Pour the mixture into the greased baking dish and use a spatula to spread it out evenly. This ensures every piece of the casserole gets equal tasty bits!
5. Cheese Topping:
Take the remaining 1/2 cup of shredded cheddar cheese and sprinkle it evenly over the top. This will create a beautiful cheesy crust when baked!
6. Bake to Perfection:
Place the dish in the preheated oven and bake for about 35 to 45 minutes. Keep an eye on it! You’ll know it’s done when the center is set and the top is a lovely golden brown.
7. Cool and Cut:
Once it’s baked, remove it from the oven and let it cool for a few minutes. Then, cut it into squares for easy serving!
8. Garnish and Serve:
If you like, you can sprinkle some freshly chopped parsley or chives on top for a pop of color and extra flavor. Serve it warm and enjoy your hearty, cheesy Bisquick Breakfast Casserole with family and friends!
Bon appétit!
Can I Use Different Proteins in This Casserole?
Absolutely! You can substitute the breakfast sausage with cooked ham, bacon, or even diced vegetables for a vegetarian option. Just ensure that any protein you use is fully cooked before adding it to the mix.
Can I Make This Casserole Ahead of Time?
Yes! You can prepare the casserole the night before. Just mix everything and pour it into the greased dish, cover with foil, and refrigerate overnight. When ready to bake, add an extra 5-10 minutes to the baking time since it will be starting cold.
How Do I Store Leftovers?
Store any leftovers in an airtight container in the fridge for up to 3 days. For longer storage, you can freeze portions for up to 2 months. When reheating, warm in the oven or microwave until heated through.
What Can I Serve with This Casserole?
This casserole pairs wonderfully with fresh fruit, a light salad, or even some crispy bacon on the side for a complete breakfast spread!



